Schematic representation of tiling. The reference sequence at the top represents a hypothetical 800 bp exon with dotted blue lines indicating the intron-exon boundaries. Hypothetical baits are 80 bp long. This example is based on a 3x tiling strategy where each nucleotide is (on average) covered by three unique baits. The bait coverage decreases towards the ends of the exon as the target design of this hypothetical example did not include introns or intergenic regions.